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Uncovering the Origins of the Commensal House Mouse
: George Shuklin When I encounter my cat fixated on specific locations in my kitchen, her behavior shows me that she has heard some mice in those areas. In fact, mice have been attributed as a reason...
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Small Changes With Large Consequences: The Role of Genetic Variance in...
Human Ferrochelatase 2 angstrom crystal structure. Generated from 1HRK (RCSB PDB) using Pymol. Copyright: Sarah Wilson / CC BY-SA Understanding how disease states arise from genetic variants is...
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Using the Power of Technology for Viral Outbreaks
Artist’s rendition of a virus particle. When the world is experiencing a viral pandemic, scientists and health officials quickly want data-driven answers to understand the situation and better...
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Identifying the Ancestor of a Domesticated Animal Using Whole-Genome Sequencing
What animal can be found around the globe that outnumbers humans three to one? Gallus gallus domesticus, the humble chicken. The human appetite for eggs and lean meat drive demand for this feathered...
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Targeting Glioblastoma Cells by Packaging a Lentiviral Vector Inside a Zika...
A recent article published in Cancers demonstrates a new method for targeting glial cells using a lentiviral packaging system that incorporated Zika virus envelope proteins. By using the reporter gene...
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Finding Signs of Cancer in Dinosaur Fossils
Centrosaurus is a herbivorous Ceratopsian dinosaur that lived in Canada in the Cretaceous Period. Did dinosaurs get cancer? That isn’t an easy question to answer. Finding and diagnosing cancer in...
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Engineering a Safer SARS-CoV-2 for Use in the Research Laboratory
SARS-CoV-2 illustration from CDC; Photo Credit: Alissa Eckert, MS; Dan Higgins, MAM E = envelope; M = membrane A worldwide pandemic requires scientific research to understand the viral pathogen. The...
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Herd Immunity: What the Flock Are You Talking About?
When it comes to blocking the spread of viral pathogens that cause human disease, epidemiologists—people who study disease outbreaks—like to talk about herd immunity. But what do they mean when...
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Toxicity Studies in Organoid Models: Developing an Alternative to Animal Testing
Alternatives to animal testing have long been explored when it comes to studying the safety of various chemical compounds for use in food, medicine and cosmetics. With the advent of three-dimensional...
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A One-Two Punch to Knock Out HIV
HIV-1 lifecycle illustration. Copyright Promega Corporation. Scientists investigating the human immunodeficiency virus (HIV) have learned much about the retrovirus’s lifecycle, but their ultimate...
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